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Acute Myeloid Leukemia

publications


ROMER-SEIBERT AND MEYER CURRENT OPINION IN HEMATOLOGY 2021

Genetic heterogeneity and clonal evolution in acute myeloid leukemia


 
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MEYER ET AL. JOURNAL of EXPERIMENTAL MEDICINE 2018

miR-196b target screen reveals mechanisms maintaining leukemia stemness with therapeutic potential

Skp2 inhibitor treatment for AML.

 

 
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sara meyer

Splicing together the origins of MDS-RS

Inside Blood commentary on Mortera-Blanco et al.

 

 
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sara meyer

From EMT to HSC to AML: ZEB2 is a cell fate switch

Inside Blood commentary on complimentary studies by J. Li et al and H. Li et al.

 

 
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meyer et aL. cancer discovery 2016

DNMT3A Haploinsufficiency Transforms FLT3ITD Myeloproliferative Disease into a Rapid, Spontaneous, and Fully Penetrant Acute Myeloid Leukemia

The first mouse model of DNMT3A/FLT3-mutant AML.

 

 

Our Team

 
 
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Sara meyer, PhD

Assistant Professor of Cancer Biology and Medical Oncology

Sidney Kimmel Cancer Center, Thomas Jefferson University

Postdoc Fellowship, Cincinnati Children's Hospital Medical Center

PhD, University of Cincinnati

 
 

melanie goetz

PhD Candidate, Biochemistry & Molecular Pharmacology Program

BS, Muhlenberg College

Melanie is studying the therapeutic utility of epigenetic drugs in AML and the clonal heterogeneity of epigenetic-mutant AML.

Melanie.Goetz@students.jefferson.edu

 
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MICHAEL LAWLER, MS

PhD Candidate, Genetics Genomics & Cancer Biology Program

MS, Thomas Jefferson University

BS, DeSales University

Mike is studying the roles of innate immune signaling pathways in AML.

Michael.Lawler@students.jefferson.edu

 
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Olivia Mowery

Research Technician

BS, La Salle University

Olivia is a research technician.

Olivia.Mowery@jefferson.edu

 

Past lab members

Sarah Broskin, MS, Research Technician (Johnson & Johnson)

Isabel Jacob, Undergradate student, Jefferson Honors Institute (Lake Erie College of Osteopathic Medicine Early Acceptance Program)

Amanda Versace, Research Assistant (University of Pennsylvania)

Holly Gamlen, BS, Drexel Master’s student (SUNY Upstate Medical University)

Jennifer Romer-Seibert, Postdoc Fellow (Analytical Biological Services)

News


Congratulations to Mike! Awarded a Travel Scholarship and platform talk at the Keystone Hematopoiesis Meeting!

January 2019


Congratulations to Jen! Awarded NCI T32 funding support!!!

December 2019


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Lab Holiday lunch 2019 & cookie swap!

We have some amazing bakers in the lab, no wonder they are also great scientists! Think there is a correlation??


 
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Our lab running with #TeamSKCC in the 8k part of Philly AACR marathon weekend

November 2019

 

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Our lab’s Halloween door entry for Cancer Biology 2019 contest!

October 2019


SKCC awards collaborative pilot project grant to the Meyer and Hou Labs!

March 2019


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Lab Holiday lunch 2018 @ Porta

Fueling up for an awesome 2019!

December 2018


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Our entry for the Cancer Biology Halloween door contest!

We got a lot of kudos for being the most creative!!!

October 2018


Congratulations to the Meyer lab and thank you to our funders for their support!!!!

NCI R01 awarded and converted to the NCI R37 MERIT Award!

Concern Foundation awarded a Conquer Cancer Now grant!

July 2018


 
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miR-196b target screen reveals mechanisms maintaining leukemia stemness with therapeutic potential

Our new study is now online and featured as the Top Story in Cancer Stem Cell News!

http://jem.rupress.org/content/early/2018/07/10/jem.20171312

 

July 2018


Philly Science March 2017

Philly Science March 2017

NERD NITE PHILLY

Sara speaking at Nerd Nite co-sponsored by the American Cancer Society.

May 2017

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ACS CAN in action!

Sara went to Capitol Hill for the American Cancer Society's Cancer Lobby Day with fellow volunteers and cancer survivors to tell Congress investing in cancer research and supporting cancer care legislation should be a National priority.

September 2017

 
 

Funding

 

NCI

R37 MERIT Award

We thank the NIH/NCI for their investment in New Early Stage Investigators and for supporting our research!

Concern Foundation

Conquer Cancer Now Award

We thank the Concern Foundation for their generous support of Young Investigator labs and support of our research!

American Cancer Society

Institutional Research Grant

Thank you to ACS for continuous support of our cancer research!

Thomas Jefferson university

Sidney kimmel cancer center

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center city, philadelphia

The NCI-designated Sidney Kimmel Cancer Center at Thomas Jefferson University and Jefferson Health is located in the heart of Center City Philadelphia, PA.

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TJU and skMc colleges

TJU's Center City campus offers a variety of educational opportunities in the Sidney Kimmel Medical College, Jefferson College of Life Sciences, Health Professions, Nursing, Pharmacy, and Population Health.

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home of the eagles

Philadelphia's Eagles NFL Champions 2018, crowds flooded Center City to celebrate the victory.


 

Contact

Sara Meyer

233 S. 10th St.

Bluemle Life Sciences Building

Sara.Meyer@jefferson.edu